Mutation Dynamics lab

As individuals age, mutations accumulate inexorably in their cells, playing a key role in evolution, ageing, and disease. Despite their importance, we still have a poor understanding of how mutations originate, or why some cells accumulate more mutations than others.

Our lab aims to understand how mutations arise—their underlying mechanisms—as well as why mutation rates vary across cell types and species. In particular, we focus on the selective pressures that drive the evolution of mutation rates.

We are based at the Institute of Evolutionary Biology in Barcelona, Spain, within the hub of the Barcelona Biomedical Research Park. Our lab is part of the Evolutionary Medical Genomics Program.

Drawing by Alex Cagan

Current funding: